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KMID : 0367419930360101458
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Journal of Korean Pediatric Society
1993 Volume.36 No. 10 p.1458 ~ p.1465
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Two Cases of Virus Associated Hemophagocytic Syndrome
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한재희
이현철/김황민/김종수/이경원
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Abstract
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Virus associated hemophagocytic syndrome, class ll histiocytoses, characterized by high fever, severe constitutional symptoms, abnormal liver function and coagulation, perigheral blood pancytopenia and histiocytic hyperplasis with prominent
hemophagocytosis in bone marrow and lymph nodes has been reported and associated with active viral infection. It is non-malignant and reversible.
It must be differentiated from histiocytic medullary reticulosis because of the inappopriateness of immunosuppressive of cytotozic therapy which is the therapeutic method for HMR, but is contraindicated in the treatment of VAHS.
This paper describes two patients whose clinicopathology was compatible with the diagnosis of virus associated hemophagocytic syndrome.
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